Intelligent and Biosensors
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An extension will develop more robust biosensor versions for use in operational environments. A further extension should target microbial pathogens associated with potential bioterrorism attacks, such as B. Further extensions to other bioterrorism bacteria and viruses are easily envisaged.
An important aim of this proposal is to develop an inexpensive, robust and compact instrument for single-molecule measurements. This aim is related to a close collaboration with SME Chelsea Technologies Group CTG , a commercial partner with extensive experience in several defense and homeland security areas. This relation with CTG will help us focus our biosensors and instruments on specific biosecurity threats; CTG also benefits from our interactions, since they are alerted of opportunities in ultrasensitive detection and biological assays.
A straight-forward extension may be a portable instrument for clinical lab or theaters of military operations. Future miniaturization that could lead to handheld instruments, which can be invaluable for first respondents in potential incidents in the urban rail networks, in inspections at ports of entry in the UK, and in monitoring the safety of water resources.
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The drive towards simpler and affordable single-molecule detection should also drive the development of similar instruments for the academic market, allowing non-physicists to gain access to ultrasensitive microscopes that detect single molecules. The biosensor platform should also offer excellent opportunities for improved health care through rapid diagnosis of infections. Applications may involve detection of microbes responsible for hospital-acquired infections e.
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The biosensor platform can improve food safety by providing means to screen for food-borne pathogens, such as enterohemorrhagic E. The potential applications in agriculture also include better monitoring of pathogens afflicting animal populations by detecting devastating viruses such as the Bluetongue virus and the virus that causes foot-and-mouth disease.
Successful biosensors along these lines may be pursued by a spin-off company, a option that can be assisted by Isis Innovation, the technology transfer arm of Oxford University. Our development of the biosensor platform and compact instrument will be communicated through the usual academic channels such as scholarly journals, departmental and group websites, press releases, and outreach efforts.
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Laboratory of Biosensors and Analytical Microsystems
Contact Location. Laboratory of Biosensors and Analytical Microsystems. Chung, T. Kuo, Y. Wang, D.
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